Staff

  • 陶涛


基本信息 Personal Information

姓名

Name

陶涛 TAO Tao

教育背景

Education Background

美国Case Western Reserve University,博士

研究方向

Research interests

长期研究蛋白质在细胞核质间转运的分子机理和功能,特别关注负责蛋白质核质转运的受体(karyopherins)家族成员在细胞分化,组织发育及疾病发生中的转录调控和翻译后修饰的分子机理和生物学意义。

职称

Title

教授(二级),博士生导师

办公室地址

Address

厦门大学翔安校区坤銮楼Kunluan Building, Xiangan Campus, Xiamen University

个人简介Personal Profile

19821986武汉大学病毒学及分子生物学系,本科
1986
1989武汉大学病毒学及分子生物学系,硕士

19891994武汉大学生命科学学院 助教,讲师

19931994武汉大学研究生院培养教育处 副处长
1995
1997美国Case Western Reserve大学医学院 访问学者
1998
2000美国Case Western Reserve大学医学院病理学系 博士

20012003加拿大McGill大学人类遗传学系 博士后
2004
-至今:厦门大学生命科学学院 教授,博士生导师

20082012:厦门大学研究生院 副院长兼学位与学科建设办公室主任

20122017厦门大学研究生院研究生院 常务副院长

11/2017-至今:厦门大学海外教育学院/国际学院 院长

学术兼职

1.Biochimica et Biophysica Acta–Molecular Cell Research 杂志

Section EditorJCR 二区,5-year impact factor(2016):5.37)

2.中国学位与研究生教育学会 理事

3.中国高等教育学会 理事

4.教育部中外合作办学项目评议专家

5."学位与研究生教育"杂志编委会委员

获奖情况

2009年 厦门大学“汪德耀”奖 (教学科研)
2009
年 厦门大学“中国银行”奖 (科研)
2010
年 福建省优秀博士论文二等奖(指导教师)
2011
年 厦门大学“田昭武学科交叉奖”一等奖 (科研)
2014
年 厦门大学“建设银行”奖 (科研)
2014
年 福建省教学成果二等奖(排名第二)

2015中国学位与研究生教育学会评估委员会突出贡献奖

2016中国学位与研究生教育学会研究生教育成果二等奖 (排名第一)

2016中国学位与研究生教育学会首届学会工作贡献奖

2016“学位与研究生教育”杂志优秀编委

主持过的国家级科研项目情况

1.国家重点基础研究发展计划(973) (#2013CB910803) 基于蛋白质相互作用网络的p53功能调控机制研究(2013/01-2017/12)

2.国家自然科学基金面上项目 (#31270810 Arx的细胞核质分布调控成肌细胞C2C12分化的分子机理研究(2013/01-2016/12)

3.国家重点基础研究发展计划 (973)(#2012CB966602) 揭示信号通路对中胚层干细胞体内自我更新和分化的生理调控机制 (2012/01-2016/12)

4.国家自然科学基金面上项目 (#81071670 PSMB6在肝癌发生中的功能研究(2011/01-2011/12)

5.国家自然科学基金面上项目 (#30971669 NLS1介导的转录因子Arx在细胞核定位的分子机理研究(2010/01-2012/12)

6.863”重大项目子课题 (#2006AA02A310) 人类肝脏蛋白质相互作用研究 (2008/01-2010/12)

7.国家自然科学基金重大研究计划 (#90608007 importin13myopodin相互作用的生物学功能研究(2007/01-2009/12)

8.国家科技攻关计划子课题 #2004BA711A19蛋白水解小体中亚基间相互作用(2005/01-2005/12)

9.国家自然科学基金项目面上项目 (#30470854)胚胎脑发育的分子机理:lgl2蛋白质的生物学功能的研究 (2005/01-2007/12)

科研成果

授权发明专利:
肌荚蛋白(Myopodin)抗体制备方法,发明人:陶涛等,2007912日授权,专利号:ZL200510119578X

发表论文Academic Paper

著作:

覃红霞,陶涛 (2017). 厦门大学研究生教育发展史厦门大学出版社 (印刷中)

代表性文章:

1.徐岚,陶涛 (2017). 跨学科研究生教育培养模式创新:以能力和身份认同为核心. 厦门大学学报(哲社版) (录用)

2. Sun S, Liu S, Zhang Z, Zeng W, Sun C, Tao T, Lin X, Feng XH (2017). Phosphatase UBLCP1 controls proteasome assembly. Open Biol. 7(5). pii: 170042. doi: 10.1098/rsob.170042

3.  Xu P, Lin W, Liu F, Tartakoff A. & Tao T. (2017).Competitive regulation of

IPO4 transcription by ELK1 and GABP.  Gene, 613, 30–38

4.  Lin W, Xu P, Guo Y, Jia Q & Tao T. (2017). Nuclear import of Nkx2-2 is

mediated by multiple pathways.  Biochem Biophys Res Commun. 482, 1511-1516

5.徐岚,陶涛,吴圣芳(2017)以学制改革为切入点的研究生培养方案修订-

门大学的行动研究. 高等教育研究38:37-47

6.徐岚,陶涛 (2016) 高水平研究生教育是双一流的突出特征.

高等教育研究37:104-109

7.高星,陶涛 (2016) 研究生科学人文素质拓展的培养体系构建探究.

学位与研究生教育282:9-13

8.徐岚,陶涛,严弋(2016)师生关系的跨文化比较研究基于过程的博士研究

生培养质量.学位与研究生教育282:62-66

9.覃红霞,陶涛,王晟(2016)中国早期研究生教育的实践-以厦门大学为例.

厦门大学学报(哲学社会科学版)233:149-156

10. Sekhri, P., Tao, T., Kaplan, F. & Zhang, X.D. (2015) Characterization of amino acid residues within the N-terminal region of Ubc9 that play a role in Ubc9 nuclear localization. Biochem. Biophys. Res. Commun.doi: 10.1016/j.bbrc.2015.01.081. [Epub ahead of print]

11. Lieu, K.G., Shim, E.H., Wang, J., Lokareddy, R.K., Tao, T., Cingolani, G., Zambetti, G.P. & Jans, D.A. (2014) The p53-induced factor Ei24 inhibits nuclear import through an importin β-binding-like domain.J. Cell Biol.205, 301-312

12. Yao, J.W., Xiao, Y., Zuo, Q.L., Zhang, Y., Tao, T. & Lin, C.J. (2013) Effectiveness of cysteine proteases on protein/pigment film removal.Arch. Oral Biol.58, 1618-1626

13. Ye, W., Lin, W., Tartakoff, A.M., Ma, Q. & Tao, T. (2013) Nuclear import of aristaless-related homeobox protein via its NLS1 regulates its transcriptional function. Mol. Cell. Biochem.381, 221-231

14. Yuan, F., Ma, Y., You, P., Lin, W., Lu, H., Yu, Y., Wang, X., Jiang, J., Yang, P., Ma, Q. & Tao, T. (2013) A novel role of proteasomal β1 subunit in tumorigenesis.Biosci. Rep.33, 555-565

15. You, P., Peng, Z., Wang, Y. & Tao, T. (2013) Expression and subcellular distribution of imp13 are regulated in brain development. In Vitro Cell. Dev. Biol. Anim. 49, 346-353

16. Xu, K., Tao, T., Jie, J., Lu, X., Li, X., Mehmood, M.A., He, H., Liu, Z., Xiao, X., Yang, J., Ma, J.X., Li, W., Zhou, Y. & Liu, Z. (2013) Increased importin 13 activity is associated with the pathogenesis of pterygium. Mol. Vis. 19, 604-613

17. Yuan, F., Lu, J., You, P., Yang, Z., Yang, P., Ma, Q. & Tao, T. (2013) Proteomic profiling of expression of proteasomal subunits from livers of mice treated with diethylnitrosamine. Proteomics13, 389-397

18. Yao, J., Lin, C., Tao, T. & Lin, F. (2013) The effect of various concentrations of papain on the properties and hydrolytic rates of β-casein layers. Colloids Surf. B Biointerfaces.101, 272-279

19. Ye, W., Lin, W., Tartakoff, A.M. & Tao, T. (2011) Karyopherins in nuclear transport of homeodomain proteins during development.Biochimica et Biophysica Acta–Molecular Cell Research 1813, 1654-1662

20. Yao, J.W., Lin, F., Tao, T. & Lin, C.J. (2011) Affinity interactions between natural pigments and human whole saliva.Arch. Oral Biol.56, 285-293

21. You, P., Ma, Q. & Tao, T. (2010) Gene diagnosis of oculopharyngeal muscular dystrophy in a Chinese family by a GeneScan method.J. Clin. Lab. Anal.24, 422-425

22. Yao, J.W., Lin, C.J., Chen, G.Y., Lin, F. & Tao, T. (2010) The interactions ofepigallocatechin-3-gallate with human whole saliva and parotid saliva.Arch. Oral Biol.55, 470-478

23. Tartakoff, A.M. & Tao, T. (2010) Comparative and evolutionary aspects of macromolecular translocation across membranes.Int. J. Biochem. Cell Biol.42, 214-219

24. Hu,R., Lin, C., Wang, H. & Tao, T. (2010) Modulation effects of collagen І on the structure of electrochemically deposited hydroxyapatite coating.

Materials Letters 64, 915-917

25. Huang, S., Chang, I.S., Lin, W.B., Ye, W., Luo, R.Z., Lu, Z., Lu, Y., Zhang, K., Liao, W.S., Tao, T., Bast, Jr R.C., Chen, X. & Yu, Y. (2010). ARHI (DIRAS 3), an imprinted tumor suppressor gene, binds to importins, and blocks nuclear import process of cargo proteins. Bioscience Reports,30,159-168

26. Wang, H., Tao, T., Tang, J., Mao, Y.H., Li, W., Peng, J., Tan, G., Zhou, Y.P., Zhong, J.X., Tseng, S.C., Kawakita, T., Zhao, Y.X. & Liu, Z.G. (2009) Importin 13 serves as a potential marker for corneal epithelial progenitor cells. Stem Cells27, 2516-2526

27. Lin, W., Ye, W., Cai, L., Meng, X., Ke, G., Huang, C., Peng, Z., Yu, Y., Golden, J.A., Tartakoff, A.M. & Tao, T. (2009) The roles of multiple importins for nuclear import of murine aristaless-related homeobox protein. J. Biol. Chem.284, 20428-20439

28. Quan, Y., Ji, Z.L., Wang, X., Tartakoff, A.M. & Tao, T. (2008) Evolutionary and

transcriptional analysis of karyopherin beta superfamily proteins.

Mol. Cell. Proteomics7, 1254-1269

29. Chen, C., Huang, C., Chen, S., Liang, J., Lin, W., Ke, G., Zhang, H., Wang, B., Huang, J., Han, Z., Ma, L., Huo, K., Yang, X., Yang, P., He, F. & Tao, T. (2008) Subunit-subunit interactions in the human 26S proteasome.Proteomics8, 508-520 cover paperhighlighted in Currents: Journal of Proteome Research, 7(4):1371

30. Liang, J., Ke, G., You, W., Peng, Z., Lan, J., Kalesse, M., Tartakoff, A.M., Kaplan, F. & Tao, T. (2008) Interaction between importin 13 and myopodin suggests a nuclear import pathway for myopodin. Mol Cell Biochem.307, 93-100

31. Wang, Y.P., Liang, L., Han, B.C., Quan, Y., Wang, X., Tao, T. & Ji, Z.L. (2006) GEPS: the Gene Expression Pattern Scanner. Nucleic Acids Res. 34 (Web Server issue), W492-497

32. Tao, T., Lan, J., Lukacs, G.L., Haché, R.J. & Kaplan, F. (2006) Importin 13 regulates nuclear import of the glucocorticoid receptor in airway epithelial cells.Am J Respir Cell Mol Biol.35, 668-680.

33. Tao, T., Lan, J., Presley, J.F., Sweezey, N.B. & Kaplan, F. (2004) Nucleocytoplasmic shuttling of lgl2 is developmentally regulated in fetal lung. Am J Respir Cell Mol Biol.30, 350-359.

34. Tao, T. &  Tartakoff, A.M. (2001) Nuclear relocation of normal huntingtin. Traffic2385-394.

35. Ono, H., Sawada, K., Khunajakr, N., Tao, T., Yamamoto, M., Hiramoto, M., Shinmyo, A., Takano, M. & Murooka, Y. (1999) Characterization of biosynthetic enzymes for ectoine as a compatible solute in a moderately halophilic eubacterium, Halomonas elongata. J. Bacteriol.181, 91-99.

36. Ma, J., Tasch, J.E., Tao, T., Zhao, J., Xie, J., Drumm, M.L. & Davis, P.B.(1996) Phosphorylation-dependent block of cystic fibrosis transmembrane conductance regulator chloride channel by exogenous R domain protein.J. Biol. Chem.271, 7351-7356.

37. Tao, T., Xie, J., Drumm, M.L., Zhao, J., Davis, P.B. & Ma, J. (1996) Slow conversions among subconductance states of cystic fibrosis transmembrane conductance regulator chloride channel. Biophysics J.70, 743-753.

38. Tao, T., Yasuda, N., Ono, H., Shinmyo, A. & Takano, M. (1992) Purificationand characterization of 2, 4-Diaminobutyric acid transaminase from Halomonas sp. Annual Reports of International Center of Cooperative Research in Biotechnology. 15, 187-199